Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review

Article Abstract:

Smokers with coronary heart disease who quit smoking can reduce their risk of premature death by as much as 36%, according to researchers who analyzed 20 studies on this topic. This means that quitting smoking can have a greater impact on outcome than many other interventions. Unfortunately, many of the studies focused on middle-aged white men and did not include the elderly, women, or ethnic minorities.

Patient outcomes, Prognosis, Coronary heart disease, Smokers, Cardiac patients, Death of

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Varenicline, an [alpha]4[beta]2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: A randomized controlled trial

Article Abstract:

A study was conducted to assess efficacy and safety of varenicline for smoking cessation compared with sustained-release bupropion (bupropion SR) and placebo. It was found that varenicline was significantly more efficient than placebo for smoking cessation at all time points and significantly more effective than bupropion SR at the end of 12 weeks of drug treatment and at 24 weeks.

Drug therapy, Varenicline

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FDA speeds smoking cessation drug review

Article Abstract:

The Food and Drug Administration (FDA) has agreed to speed its review of an experimental smoking cessation drug called varenilcline that studies suggest is more effective at helping smokers quit than bupropion. The drug specifically targets the brain receptors responsible for mediating the reinforcing effects of nicotine.

United States, Care and treatment, Risk factors, United States. Food and Drug Administration

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