Obesity and prognosis in endometrial cancer

Article Abstract:

Women with uterine cancer who are very obese may have a better chance of survival than women who are less obese or of normal weight. Researchers studied 492 women with uterine cancer and correlated the survival outcome with the Quetelet index, a measure of obesity. Very obese women with a Quetelet index over 40 were found to have less aggressive cancer and 4.8% cancer-positive lymph nodes. Obese women with a Quetelet index of 30 to 40 had 13.2% positive lymph nodes, and women with an index below 30 had 10.5% positive nodes. Obese women had lower grade and stage tumors which were better defined than those of more slender women. Slender women may experience more aggressive cancer, and may benefit from lymph node analysis more than obese women may.

Health aspects, Patient outcomes, Mortality, Prognosis, Obesity, Cancer patients, Endometrial cancer

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Biodegradable microspheres containing group B Streptococcus vaccine: immune response in mice

Article Abstract:

A vaccine against group B Streptococcus (GBS) produced a significant antibody response when injected into mice. The vaccine is composed of GBS antigen encapsulated in biodegradable microparticles along with a cytadine-phosphate-guanosine adjuvant. The vaccine produced antibodies that would protect both a pregnant woman and her baby from GBS infection.

Evaluation, Streptococcal infections, Prevention, Bacterial vaccines

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Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere

Article Abstract:

Most strains of group B streptococci are still susceptible to penicillin, according to researchers who analyzed blood samples from 122 people with the infection. However, 25% of the strains were resistant to erythromycin and 7% were resistant to clindamycin.

Statistics, Drug resistance in microorganisms, Microbial drug resistance, Streptococcus agalactiae

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