Toward molecularly based diagnostics for the oral cavity

Article Abstract:

Saliva may be useful in medical diagnostic and screening tests. Saliva contains blood cells, ions, chemicals, antibodies, enzymes, and waste products. Tests are already available to test saliva for Porphymonas gingivalis, which causes periodontal disease, to assess susceptibility to dental decay. Detection of microbial antigens or antibodies in saliva may permit disease diagnosis and DNA testing, and saliva may be used in illicit drug screening and blood alcohol tests. These tests are noninvasive, reducing pathogen exposure risks to health care workers.

Methods, Medical examination, Saliva, Diagnosis, Noninvasive, Noninvasive diagnosis

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Toward a common theme for autoimmunity

Article Abstract:

Autoimmune diseases are chronic conditions resulting from the inappropriate immune system recognition and attack of normal organs, tissues, and substances in the body. The immune system's chief role is to differentiate "self" from "foreign," then isolate and destroy nonself materials. In autoimmunity, antibodies against "self" form immune complexes that damage organs and tissues progressively. Rheumatoid arthritis, systemic lupus erythematosus, type 1 diabetes, and scleroderma are autoimmune diseases.

United States, Physiological aspects, Autoimmune diseases

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A personal change and a changing panorama: looking toward the next decade

Article Abstract:

The director of the National Institute of Dental and Craniofacial Research gives his forecast of the changes that will affect dentistry in the 21st century. On July 14, 2000, he will leave his position to become the dean of the School of Dentistry at the University of Southern California.

Forecasts and trends, Dentistry

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