The prevalence and significance of occult hepatitis B virus in a prospective cohort of HIV-infected patients

Article Abstract:

The prevalence of occult hepatitis B virus (HBV) in the HIV-infected population at the University of Cincinnati HIV clinical center was determined to characterize the associations between occult infection, transaminase elevations, and ART. The HBV patients might remain unidentified for years until symptoms develop, and even then, elevated alanine/aspartate aminotransferase (ALT/AST) levels might be misattributed to ART-related hepatotoxicity if no other evidence of viral hepatitis is present.

Health aspects, Prevention, Risk factors, Medical examination, HIV patients, Hepatitis B virus, Clinical report

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Micro RNA and HIV

Article Abstract:

Rosetta's micro-RNA (miRNA) detection methodology is based on a bioinformatics miRNA screening of the whole genome followed by biologic validation, which uses miRNA chips and sequence-directed cloning and sequencing. The analysis of HIV genome revealed several candidate hairpin structures in the HIV genome, through the generation of cDNA libraries from small-size RNA of HIV-infected cells.

Science & research, Research, HIV infection, HIV infections, Nucleotide sequence, Base sequence, Messenger RNA

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