Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients

Article Abstract:

In this large, randomized, placebo controlled trial, peginterferon Alfa-2a plus ribavirin elicited significantly higher rates of sustained virologic response than interferon Alfa-2a plus ribavirin in patients infected with both HIV and HCV. The combination of peginterferon Alfa-2a plus ribavirin was significantly more effective than either interferon Alfa-2a plus ribavirin or peginterferon Alfa-2a monotherapy.

Drug therapy, HIV (Viruses), HIV, Dosage and administration, Drug therapy, Combination, Combination drug therapy, Comorbidity, Hepatitis C virus, Ribavirin (Medication)

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Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites

Article Abstract:

A study was conducted to compare the rates of response to treatment with peginterferon alfa-2b and ribavirin among African Americans and non-Hispanic whites with chronic hepatitis C. The result shows a lower rate of response to the treatment in African Americans than non-Hispanic white patients.

Health aspects, Care and treatment, African Americans, Interferon alpha, Ribavirin

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Autoimmune hepatitis

Article Abstract:

Autoimmune hepatitis is a generally progressive, chronic disease with occasionally fluctuating activity that occurs worldwide in children and adults. Although the cause of autoimmune hepatitis is unknown, aberrant autoreactivity is thought to have a role in its pathogenesis.

England, Genetic aspects

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