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Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation

Article Abstract:

Increased blood levels of homocysteine may be a risk factor for preeclampsia. Preeclampsia is a complication of pregnancy characterized by high blood pressure and abnormal blood clotting. Researchers measured homocysteine in blood samples from 33 women with normal pregnancies and 21 with a pregnancy complicated by preeclampsia. Homocysteine levels were higher in women with preeclampsia. Homocysteine is a risk factor for heart disease because it is associated with abnormal blood vessel function. It may play the same role in preeclampsia.

Author: Roberts, James M., Ness, Roberta B., Crombleholme, William R., Powers, Robert W., Evans, Rhobert W., Majors, Alana K., Ojimba, Jacqueline I.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
Physiological aspects, Homocysteine

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Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery

Article Abstract:

The changes in serum uric acid across pregnancy in women with gestational hyperuricemia at delivery, with and without preeclampsia, compared with normal pregnant and women with preeclampsia without gestational hyperuricemia are investigated. It is found that elevations in uric acid occur early in women with hyperuricemia at delivery, thus concluding that many multimechanisms can contribute to increased uric acid including changes in renal function.

Author: Roberts, James M., Ness, Roberta B., Bodnar, Lisa M., Powers, Robert W., Cooper, Katheryn M., Gallaher, Marcia J., Frank, Michael P., Daftary, Ashi R.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
United States, Pregnant women, Hyperuricemia

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Urinary cotinine concentration confirms the reduced risk of preeclampsia with tobacco exposure

Article Abstract:

Smoking appears to lower the risk of preeclampsia, a serious complication of pregnancy. By measuring a metabolite of nicotine in the urine of 100 pregnant women, researchers found that women who smoked were 70% less likely to develop preeclampsia.

Author: Roberts, James M., Ness, Roberta B., Krohn, Marijane A., Crombleholme, William R., Powers, Robert W., Lain, Kristine Y.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
Prevention, Smoking

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Subjects list: Preeclampsia, Health aspects
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