Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease

Article Abstract:

An international randomized trial compared oral posaconazole with oral fluconazole for prophylaxis against invasive fungal infections in patients with graft-versus-host disease (GVHD) receiving immunosuppressive therapy. Results indicated that posaconazole was similar to fluconazole for prophylaxis against fungal infections, but was superior in preventing invasive aspergillosis and reducing the rate of deaths related to fungal infections.

Drug therapy, Dosage and administration, Mycoses, Fluconazole

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Case 35-2007: a 30-year-old man with inflammatory bowel disease and recent onset of fever and bloody diarrhea

Article Abstract:

A case study of a 30-year-old Moroccan man with history of inflammatory bowel disease and fever, abdominal pain and bloody diarrhea is reported. The patient was diagnosed with acute CMV (cytomegalovirus) infection with inflammatory bowel disease and recommended for further test data to determine the efficacy of treatment with antiviral prophylaxis and immunosuppressive agents.

Usage, Diagnosis, Cytomegalovirus infections, Inflammatory bowel diseases, Immune system, Immunologic tests, Case study

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Prophylaxis for thromboembolism in hospitalized medical patients

Article Abstract:

A 62-year-old man is admitted to a hospital with fever, cough, and dyspnea, whose further testing offers a diagnosis of venous thromboembolism. The symptoms and management of the condition are discussed, including the question of whether thromboprophylaxis should be provided to the patient and, if so, what form it should take.

Case studies, Thromboembolism

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