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Prevalence of infective endocarditis in patients with systemic lupus erythematosus

Article Abstract:

A significant minority of patients with systemic lupus erythematosus (SLE) have detectable heart murmurs that may predispose them to infective endocarditis following dental and other invasive medical procedures. SLE is an autoimmune disease that sometimes causes heart valve abnormalities. Valve disease increases the risk of heart infections following procedures which might introduce bacteria into the bloodstream, such as dental cleaning and surgery. Researchers reviewed the medical charts of 275 SLE patients, and found that 19% had a heart murmur indicating a possible valve defect. About 4% of these patients had valve defects, and might benefit from antibiotics during invasive procedures.

Author: Miller, Craig S., Falace, Donald A., Rayens, Mary Kay, Egan, Rita M., Moore, Charles R.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 1999
Complications and side effects, Risk factors, Systemic lupus erythematosus, Endocarditis, Bacterial, Bacterial endocarditis, Dental prophylaxis

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The efficiency of valacyclovir in preventing recurrent herpes simplex virus infections associated with dental procedures

Article Abstract:

The efficacy and safety of oral valacyclovir in suppressing dentally related cold sore outbreak and herpes simplex virus (HSV) shedding is determined. HSV recrudescence after routine dental treatment is suppressed by valacyclovir prophylaxis.

Author: Miller, Craig S., Cunninggham, Larry L., Lindroth, John E., Avdiushko, Sergei A.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 2004
Drug therapy, Dosage and administration, Herpes simplex virus, Valacyclovir

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Salivary biomarkers of existing periodontal disease

Article Abstract:

A study examining the correlation between salivary biomarkers, specific to inflammation, collagen degradation and bone turnover and periodontal disease, is presented.

Author: Miller, Craig S., Kryscio, Richard J., Jr., King Charles P., Langub, Chris, Thomas, Mark V.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 2006
Periodontal disease, Periodontal diseases, Biological markers

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Subjects list: United States, Research
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