Preventing and treating rhinitis medicamentosa

Article Abstract:

Overuse of nasal decongestant sprays can cause rebound congestion, declining effectiveness, and nasal irritation known as rhinitis medicamentosa (RM). Chronic use of nasal sprays and other topical vasoconstrictors, such as oxymetazoline and the street drug cocaine, can lead to septal perforation from ischemia. Patients with RM often report congestion unresponsive to medication, and may have inflammation and bleeding. Patients may be weaned from nasal sprays one nostril at a time, aided with saline or steroid sprays, Dexacort Phosphate Turbinaire, or mechanical nasal dilators. Nasal decongestant sprays should only be used for 3-7 days.

Causes of, Complications and side effects, Rhinitis, Decongestants

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Treating Alzheimer's Disease with Cholinergic Drugs, Part 2

Article Abstract:

Donepezil has been shown to be an effective treatment for mild to moderate Alzheimer's disease. This drug is well tolerated, although it can produce mildly adverse gastric effects, irregular heartbeat, muscle cramps and dizziness. Similar results apply to metrifonate, a drug expected to be approved in 1999.

Drug therapy, Alzheimer's disease, Anti-Alzheimer's disease agents

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