Procedure-related fetal losses in transplacental versus nontransplacental genetic amniocentesis

Article Abstract:

The miscarriage rate subsequent to amniocentisis is not affected if the needle passes through the placenta. Records were reviewed from 1000 procedures. In 518 cases the placenta was implanted on the front side of the uterus, and in 306 amniocenteses the needle passed through the placenta. Thirteen miscarriages occurred after the procedure. Loss rates were similar between groups. This contradicts results from some other studies. However, amniocenteses in this study were performed by experienced clinicians using high quality ultrasound equipment to visualize the procedure as it took place. Care was taken to pass the needle through the thinnest point of the placenta distant from where the umbilical cord joins it and to avoid piercing blood vessels or sinuses.

Complications and side effects, Fetal death

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Operator experience and sample quality in genetic amniocentesis

Article Abstract:

A study is carried out to evaluate the frequency of maternal cell contamination in amniotic fluid samples that are submitted to a single laboratory for cytogenic analysis to the experience and training of the physician who performed the amniocentesis. It is found that maternal cell contamination occurs more frequently in genetic amniocentesis samples that are obtained by physicians who perform <50 genetic amniocenteses annually.

United States, Science & research, Research, Methods

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Obstetrician-gynecologists performing genetic amniocentesis may misleading themselves and their patients

Article Abstract:

Amniocentesis is more likely to cause a miscarriage if performed by an obstetrician-gynecologist rather than a perinatologist. A perinatologist is a specialist in fetal diseases. In a study of 1,384 amniocentesis procedures, the miscarriage rate was 1 in 46 procedures for the OB/GYNs and 1 in 312 procedures for the perinatologists.

Miscarriage, Complications

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