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Procurement and allocation of solid organs for transplantation

Article Abstract:

The success of organ transplants and the increased demand for them has led to efforts to increase the supply. As of October, 1996, 49,223 people were waiting for an organ transplant. Most transplants come from people who are brain dead but have a functioning cardiovascular system. Those whose hearts have stopped are also candidates for donation. Newer techniques include taking organs from living related and unrelated donors. The 1984 National Organ Transplant Act created the United Network for Organ Sharing (UNOS), which oversees 866 organ transplant programs and 69 organ procurement organizations in the US.

Author: Hauptman, Paul J., O'Connor, Kevin J.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Analysis, Donation of organs, tissues, etc., Tissue donation

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Use of nesiritide before and after publications suggesting drug-related risks in patients with acute decompensated heart failure

Article Abstract:

Studies were conducted to evaluate the use of nesiritide before and after March and April 2005 publications in two high-impact journals that suggested an increased risk of renal failure and mortality with intravenous nesiritide for acute decompensated heart failure. It was found that nesiritide use decreased sharply after publication of data that questioned its safety and that further analyses are required to evaluate the consequences of these changes on patient outcomes.

Author: Hauptman, Paul J., Schnitzler, Mark A., Swindle, Jason, Burroughs, Thomas E.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Nesiritide

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Statin therapy and risks for death and hospitalization in chronic heart failure

Article Abstract:

The association between initiation of Statin therapy and risks for death and hospitalization among adults with chronic heart failure is evaluated. Among adults diagnosed with heart failure who had prior statin use, incident statin use is independently associated with lower risks of death and hospitalization than among patients with or without coronary heart disease.

Author: Lo, Joan C., Go, Alan S., Gurwitz, Jerry H., Lee, Wendy Y., Jingrong Yang
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
United States, Statins, Clinical report

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Subjects list: Health aspects, Usage, Risk factors, Heart failure
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