Progress in Understanding Ventilator-Induced Lung Injury

Article Abstract:

The mechanical ventilator intended to save the life of patients with acute respiratory distress syndrome (ARDS) may sometimes hasten their death. Researchers believe that mechanical ventilation with cycles of large volumes of air may accelerate the lung damage of ARDS, causing ventilator-induced lung injury. Patients with ARDS have inflamed lungs with collapsed air sacs and poor gas exchange. Ventilation with large volumes of air may subject portions of the lungs to very high pressures, creating additional damage. Positive end-expiratory pressure (PEEP) and other protective measures may reduce the incidence of ventilator-induced lung injury.

Health aspects, Editorial, Complications and side effects, Artificial respiration, Mechanical ventilation, Ventilators, Ventilators (Medical equipment)

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Clinicopathological features of and risk factors for multiple primary melanomas

Article Abstract:

A study was conducted to determine the incidence of multiple primary melanomas (MPM) from a prospective, single-institution, multidisciplinary database, and to describe the clinical and pathological characteristics and risk factors specific to these patients. The incidence of MPM is found to increase in patients with a positive family history or dysplastic nevi, thus recommending intensive dermatologic screening and genetic testing.

Science & research, Research, Genetic screening, Genetic testing, Melanoma

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Effects of systematic prone positioning in hypoxemic acute respiratory failure: A randomized controlled trial

Article Abstract:

The main objective of the study was to determine whether prone positioning improves mortality in acute respiratory failure (ARF) patients. It placed patients with acute lung injury in the prone position but demonstrated no beneficial outcomes and some safety concerns associated with prone positioning.

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