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Proinflammatory and type 1 cytokine expression in cervical mucosa during HIV-1 and human papillomavirus infection

Article Abstract:

The role of inflammation in HIV transmission in investigated by studying the infectious and inflammatory milieu in cervical mucosa from HIV-1- and human papillomavirus (HPV)-coinfected and HPV-monoinfected women. The results have indicated the persistence of immune activation and inflammation in the genital tract of women with HPV monoinfection and in HIV-infected women coinfected with HPV.

Author: Patterson, Bruce K., Behbahani, Homira, Landay, Alan, Spetz, Anna-Lena, Anderson, Jan, Garcia, Patricia, French, Audrey L., Walther-Jallow, Lilian, Klareskog, Elin, Baum, Linda
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
Health aspects, HIV infection, HIV infections, Inflammation, Cervix uteri, Cytokines, Clinical report

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Methylation of human papillomavirus genomes in cells of anal epithelia of HIV-infected men

Article Abstract:

Intra-anal malignancies disproportionately affect individuals who engage in anal intercourse because of infection with human papillomaviruses (HPVs) with an increased risk attributed to infection with HIV because of a declining immunity against HPVs. The combination of a high load of HPV genomes with DNA methylation may be useful marker to detect clones of malignantly progressing cells.

Author: Wiley, Dorothy J., Jian Yu Rao, Goetz, Matthew, Masongsong, Emmanuel, Bernard, Hans-Ulrich, Huh, John, Chang, Christopher, Poulter, Melinda, Ching I. Chang
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
Methylation, Anal intercourse

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High-resolution analysis of Genomic alterations and human papillomavirus integration in anal intraepithelial neoplasia

Article Abstract:

Microarray-based comparative genome hybridization (aCGH) with human inserts in bacterial artificial chromosomes (BCAs) as spotted targets were used to characterize copy number abnormalities (CNAs) in AIN tissues. Quantitative real-time polymerase chain reaction (PCR) analysis was performed to delineate an amplicon found on chromosome arm 3q better.

Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
Analysis, Polymerase chain reaction, Artificial chromosomes, Disease/Disorder overview

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Subjects list: Research, Risk factors, Papillomavirus infections, Diagnosis
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