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Radiation Therapy for Clinically Localized Prostate Cancer: A Multi-institutional Pooled Analysis

Article Abstract:

External beam radiation treatment can lead to cures in men with prostate cancer who have initial prostate-specific antigen (PSA) levels of 20 or less. This was the conclusion of a follow-up of 1,765 men with prostate cancer who received radiation treatment between 1988 and 1995. The doctors continued to monitor blood PSA levels after treatment to detect a relapse. Of the men whose initial PSA level before treatment was less than 20, 87% had stable PSA levels and no sign of disease up to five years after treatment.

Author: Zietman, Anthony L., Kuban, Deborah A., Hanks, Gerald E., Shipley, William U., Hancock, Steven L., Perez, Carlos A., Thames, Howard D., Sandier, Howard M., Smith, Cyndi D.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Evaluation, Prognosis

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Frequency and effect of adjuvant radiation therapy among women with stage I endometrial adenocarcinoma

Article Abstract:

The frequency and effect of adjuvant Radiation Therapy (RT) on overall and relative survival within the large US population was evaluated on 21,249 women's. Of 21,249 women's, 4080 received adjuvant RT and 17,169 did not receive adjuvant RT while the study also revealed a statistically significant association between improved overall and relative survival and adjuvant RT in stage IC disease.

Author: Lee, Christopher M., Szabo, Aniko, Shrieve, Dennis C., MacDonald, O. Kenneth, Gaffney, David K.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Adenocarcinoma, Women patients

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Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: A randomized controlled trial

Article Abstract:

A study evaluated the hypothesis that increasing the radiation dose delivered to men with clinically localized prostate cancer improves disease outcome. Results suggested that the patients had a lower risk of bio-chemical failure if they received high-dose rather than conventional-dose conformal radiation.

Author: Zietman, Anthony L., Shipley, William U., DeSilvio, Michelle L., Slater, Jerry D., Miller, Daniel W., Adams, Judith A., Rossi, Carl J., Jr.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Clinical trials, Men, Men's health

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Subjects list: Prostate cancer, Radiotherapy, Health aspects, Care and treatment, United States
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