Measurement of fetal nasal width by ultrasonography

Article Abstract:

Fetal nasal diameters as measured on ultrasound may be a useful supplemental strategy for identifying fetuses with genetic abnormalities such as trisomy 21 that have characteristic nasal features. Ultrasound images were used to measure and document fetal nasal diameters of 782 normal white fetuses ranging in age from 13.8 to 40.4 weeks. Measurements were used to generate a normal nasal width curve by gestational age. The 10 fetuses identified with trisomy 21 had nasal width diameters greater than one standard deviation away from the curve.

Ultrasound imaging, Diagnosis, Measurement, Down syndrome, Fetal monitoring, Nose

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Prenatal diagnosis of Kell blood group genotypes: KEL1 and KEL2

Article Abstract:

Two genetic tests on amniotic fluid samples appear to be useful in identifying different Kell genetic blood group types before birth. Some Kell blood types are associated with blood diseases in newborns. Fifteen amniotic fluid samples were tested with two genetic tests to identify Kell subtypes and then compared with blood tests on the corresponding newborn. The genetic tests done on the amniotic fluid samples agreed with the blood tests done on the corresponding newborns.

Analysis, Genotype, Genotypes, Blood groups, ABO blood-group system

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