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Recombinant human leptin in women with hypothalamic amenorrhea

Article Abstract:

In this prospective, interventional study of 8 women with hypothalamic amenorrhea, leptin administration led to normalization of levels of reproductive hormones, follicular development, and menstrual cyclicity. Leptin administration for the relative leptin deficiency in women with hypothalamic amenorrhea appears to improve reproductive, thyroid, and growth hormone axes and markers of bone formation.

Author: Welt, Corrine K., Chan, Jean L., Murphy, Robyn, Smith, Patricia
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Risk factors, Hypothalamic hormones

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Body fat, leptin, and hypothalamic amenorrhea

Article Abstract:

Hypothalamic amenorrhea may be preceded by a history of irregular menses and may last several months to years. The study by welt et al., suggests that leptin is important in mediating the neuroendocrine abnormalities of hypothalamic amenorrhea.

Author: Ahima, Rexford S.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Leptin, Hypothalamus

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A bitter tale

Article Abstract:

The case of a 53-year old woman presented to an outpatient urgent care clinic with persistent nausea and omitting is discussed. Accidental digitalis toxicity associated with consumption of plants that contain cardiac glycosides is diagnosed.

Author: Newman, Lori S., Feinberg, Mark W., LeWine, Howard E.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Diagnosis, Nausea, Vomiting, Cardiotonic agents, Cardiac glycosides

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Subjects list: Health aspects, Care and treatment, Research, Women, Menstruation disorders
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