Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

Article Abstract:

The application of indirect propriospinal relay connections in the recovery of supraspinal control of stepping after spinal cord injury (SCI) is discussed. The analysis reveals various therapeutic strategies for the restoration of different functions after SCI by bypassing lesions without regeneration from the brain.

Neurons, Neuroplasticity

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Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?

Article Abstract:

An argument on whether non-human primates make a better model than rodents in experiments for testing the efficacy of functional recovery after spinal cord injury in humans is presented. It was concluded that non-human primates provide a better translation of treatments for spinal cord injury in humans.

Physiological aspects, Primates

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cAMP and schwan cells promote axonal growth and functional recovery after spinal cord injury

Article Abstract:

Activation of cAMP signaling can effectively induce neurons to overcome inhibitory signals. Modulation of neuronal cAMP levels in combination with autologous SC transplantation can have significant implications on therapeutic intervention in improving outcome after human SCI.

Causes of, Risk factors, Growth, Axons, Schwann cells, Company growth

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