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Regulation of immune response by T cells

Article Abstract:

The regulation of immune response by the T-cells and the way they mediate the peripheral regulatory mechanism and intrinsic homeostatic mechanisms are examined. The T cells that are reactive with tumors express intermediate-avidity T-cell receptors, while the CD8+ suppressor T-cell pathway targets these antitumor T cells and interfere with successful induction of antitumor immunity.

Author: Chess, Leonard, Hong Jiang
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
T cells

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Tolls and beyond: Many roads to vaccine immunity

Article Abstract:

The article discusses on the findings of Gavin and group, that toll-like receptors (TLRs), a subclass of pathogen recognition receptors are able to induce adaptive immunity but TLRs are not necessary for vaccine-induced immune response since involvement of other pathogen recognition receptors were demonstrated.

Author: Pulendran, Bali
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Care and treatment, Bacterial infections, Bacterial vaccines

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Collaboration, genetic associations, and lupus erythematosus

Article Abstract:

The genetic and environmental factors that could cause the development of systemic lupus erythematosus (SLE) an autoimmune disease are discussed.

Author: Crow, Mary K.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2008
Editorial, Development and progression, Genetic aspects, Systemic lupus erythematosus, Single nucleotide polymorphisms

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Subjects list: Health aspects, Research, United States, Immune response
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