Research involving cognitively impaired adults

Article Abstract:

A doctor discusses the problem of obtaining informed consent from patients with intellectual impairments when conducting clinical trials and provides suggestions for overcoming this obstacle. Topics include assent, dissent, and advance informed consent, proxy decision making, and reasonable research risks. Federal laws require doctors to implement additional safeguards when treating these patients, but most state laws do not say who is legally authorized to give such consent if the patient is unable to do so.

Clinical trials, Informed consent (Medical law), Informed consent, Cognition disorders, Cognitive disorders

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The 50th anniversary of the discovery of immunologic tolerance

Article Abstract:

A scientist who co-authored the 1953 paper on immunological tolerance discusses the research that led up to this important discovery. Immunological tolerance means a person's immune system does not attack his or her own body. Research on immunological tolerance is important because doctors must find ways to minimize the immune system's reaction to a transplanted organ. In other words, the immune system must learn to accept the transplanted organ.

History, Immunological tolerance, Immunologic tolerance, Immunological research, Immunologic research

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Neuronal regeneration after stroke

Article Abstract:

Human and animal research has shown that the brain can repair itself to a certain extent when it is damaged. This happens because the brain contains stem cells that can move to injured areas and grow into mature nerve cells. Although the mechanism is very complex, further research could harness this self-healing ability to treat stroke patients.

Physiological aspects, Stroke (Disease), Stroke, Nervous system, Nerve regeneration

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