Risk factor for symptomatic mitochondrial toxicity in HIV/hepatitis C virus-coinfected patients during interferon plus ribavirin-based therapy

Article Abstract:

The incidence, clinical features, and risk factors for symptomatic mitochondrial toxicity in HIV/hepatitis C virus (HCV)-coinfected patients receiving anti-HCV therapy are evaluated. The results suggest that coadminstration of ribavirin and didanosine should be avoided, and if unavoidable, the patients should be monitored closely for mitochondrial toxicity.

United States, Dosage and administration, Didanosine, Ribavirin, Hepatitis C virus

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Restoration of cellular immunity against tuberculosis in patients coinfected with HIV-1 and tuberculosis with effective antiretroviral therapy: assessment by determination of CD69 expression on T cells after tuberculin stimulation

Article Abstract:

Doctors should be cautious about discontinuing anti-tuberculosis drugs in HIV patients who are taking AIDS drugs even if their immune system seems to recover. In a study of 13 HIV patients, cellular immunity against tuberculosis did not increase even though they were taking AIDS drugs.

Research, Physiological aspects, Tuberculosis, Immunity, Immunity (Physiology)

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Clinical spectrum, morbidity, and mortality of acquired immunodeficiency syndrome in Taiwan: a 5-year prospective study

Article Abstract:

The use of highly active antiretroviral therapy (HAART) in Taiwan has cut the mortality rate from AIDS by more than 50%. HAART has been provided free of charge to many AIDS patients since 1997.

Taiwan, Health aspects, Statistical Data Included, Patient outcomes, Mortality, AIDS (Disease)

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