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Comparison of Roche Cobas Amplicor and Abbott LCx for the rapid detection of Chlamydia trachomatis in specimens from high-risk patients

Article Abstract:

The Cobas Amplicor testing system appears to be somewhat more accurate at detecting chlamydia infections than the LCx testing system. Tests for chlamydia were performed on 204 high-risk male urine samples and 98 high-risk female cervical swab samples using both systems. The probability of detecting true positive results was 100% using the Cobas Amplicor system but only 74.1% using the LCx system. The probability of detecting true negative results was 99.4% using the Cobas Amplicor system but 100% using the LCx system.

Author: Steingrimsson, Olafur, Jonsdottir, Kristin, Olafsson, Jon Hjaltalin, Karlsson, Sigfus M., Palsdottir, Rannveig, Davidsson, Steingrimur
Publisher: American Venereal Disease Association
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1998
Polymerase chain reaction

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How Adequate is Adequate for the Collection of Endocervical Specimens for Chlamydia trachomatis Testing?

Article Abstract:

The more cells that are present in a cervical specimen, the better the chance of detecting chlamydia infection. Researchers evaluated the adequacy of 3,500 cervical specimens by counting the number of cells in the specimen. The specimens were also tested for chlamydia. As the number of cells in the specimen increased, so did the number of specimens that tested positive for chlamydia.

Author: BEEBE, JAMES L., GERSHMAN, KENNETH A., KELLEY, JAMES K., HAGNER, DINAH, CREEDE, PAUL
Publisher: American Venereal Disease Association
Publication Name: Sexually Transmitted Diseases
Subject: Health
ISSN: 0148-5717
Year: 1999
Medical examination, Vaginal smears

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Subjects list: Diagnosis, Chlamydia infections
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