Subfulminant liver failure and severe hepatotoxicity caused by loratadine use

Article Abstract:

Loratadine therapy may, in rare instances, result in serious liver damage. Two patients with no history of liver disease took loratadine for allergies and later developed liver damage. Signs of liver damage developed within three weeks of treatment in one patient. These symptoms subsided when treatment stopped. Doctors removed the second patient's gall bladder after 14 months of treatment with loratadine and two months of abdominal pain. Liver damage continued even after this surgery and stopping loratadine treatment. The patient later required a liver transplant.

Complications and side effects, Antihistamines, Loratadine

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Hydrazine, cancer, the Internet, isoniazid, and the liver

Article Abstract:

Hydrazine may be the ultimate cause of the liver toxicity attributed to the tuberculosis drug isoniazid. Hydrazine is a metabolite of isoniazid, and a report published in 2000 shows that hydrazine can cause fatal liver and kidney toxicity.

Editorial

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Liver and kidney failure in a patient who used hydrazine sulfate as an alternative treatment for cancer

Article Abstract:

A man died from liver and kidney failure after taking hydrazine he had bought on the Internet to self-treat his cancer. Cancer patients should be cautious about using alternative treatments purchased on the Internet.

Acute renal failure, Acute kidney failure

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