Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

Article Abstract:

Lowering total blood cholesterol levels and levels of low-density lipoprotein (LDL) cholesterol reduces the risk of coronary heart disease according to the second report by the National Cholesterol Education Program. The second report contains updated guidelines for cholesterol management. Like the first report, it emphasizes diet therapy as the primary method of lowering cholesterol. The second report, however, stresses the importance of assessing individual risk for heart disease in determining the proper strategy for intervention. It also recognizes that higher levels of high-density lipoprotein cholesterol reduce the risk of heart disease. The second report emphasizes the importance of exercise and weight control as components of dietary therapy. Drug therapy should be considered for patients at high risk of heart disease who do not respond to dietary therapy.

Health aspects, Risk factors, Cholesterol, LDL, Coronary heart disease, VLDL cholesterol lipoproteins, Cholesterol, HDL, HDL cholesterol lipoproteins, Blood cholesterol

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An Evidence-Based Assessment of the NCEP Adult Treatment Panel II Guidelines

Article Abstract:

Several large clinical trials published in the mid to late 1990s have confirmed the recommendations in the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, which was published in 1993. At that time, drugs called statins had been introduced but not extensively tested. Consequently, the guidelines recommended nicotinic acid and bile acid sequestrants over statins. But evidence collected since 1993 shows that statins are very effective in reducing high blood cholesterol levels.

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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)

Article Abstract:

An updated version of the guidelines for treating high cholesterol levels is presented. Treatment will depend not only on cholesterol levels but other risk factors for heart disease, such as hypertension, smoking, family history, obesity, physical inactivity, and diabetes.

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