Prognostic factors of combined viral load and CD4+ cell count responses under triple antiretroviral therapy, Aquitaine Cohort, 1996-1998

Article Abstract:

Highly active antiretroviral therapy (HAART) may suppress the virus without increasing CD4+ T cell counts or increase CD4+ T cell counts without suppressing the virus. HIV RNA levels, age, pretreatment, and saquinavir therapy determined which type of response predominated.

Physiological aspects, Viremia, Anti-HIV agents

---

Survival after AIDS-defining events in patients with fewer than 200 lymphocytes CD4+ x 10(super)6/L who are toxoplasmosis antibody positive

Article Abstract:

Certain opportunistic infections appear to increase the risk of death in some AIDS patients. Researchers followed 187 HIV-infected patients who tested positive for toxoplasmosis and had CD4 T cell levels below 200 but had no AIDS-defining event. A 10-year increase in age doubled the risk of death in these patients and a further decline in CD4 counts also increased the risk slightly. However, infection with Pneumocystis, cytomegalovirus or toxoplasmosis all increased the risk of death 10-fold.

Pneumocystis carinii pneumonia, Cytomegalovirus infections, AIDS (Disease), Toxoplasmosis

---

Rapid change in the use of antiretroviral agents and improvement in a population of HIV-infected patients: France, 1995 to 1997

Article Abstract:

More French physicians are prescribing triple AIDS drug therapy with protease inhibitors and the health of AIDS patients has improved as a result. Researchers used a hospital-based information system to track changes in prescriptions and the health of HIV patients between 1995 and 1997. The number of patients who were treated increased and more were taking two or more drugs. By 1997, protease inhibitors accounted for 40% of the prescriptions. Eighteen months after the introduction of protease inhibitors, the incidence of AIDS dropped 47% and the mortality rate dropped 56%.

Analysis, Usage, Drug therapy, Prescription writing, HIV patients, Antiviral agents

Similar abstracts:

• Abstracts: Intrathecal baclofen for the treatment of dystonia in patients with reflex sympathetic dystrophy. Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy
• Abstracts: End-tidal carbon monoxide measurements in women with pregnancy-induced hypertension and preeclampsia. Neonatal hyperbilirubinemia
• Abstracts: Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema
• Abstracts: Differential alterations in responsiveness in particulate and soluble guanylate cyclases in pregnant guinea pig myometrium
• Abstracts: Preterm delivery in women with pregestational diabetes mellitus or chronic hypertension relative to women with uncomplicated pregnancies

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.