Testing for in utero immunodeficiency virus infection with fetal blood sampling

Article Abstract:

Testing the fetus for human immunodeficiency virus (HIV) infection early in pregnancy probably would not be helpful in making decisions regarding continuing the pregnancy. It is probable that HIV transmission occurs later in pregnancy. Researchers tested the blood of 28 mid-term fetuses with HIV-positive mothers before the pregnancies were terminated. Confirmation tests for HIV were also performed on the blood and thymus of these fetuses after pregnancy termination. All of the tests on fetal samples were negative for HIV. The same tests were used to confirm the HIV infection in the mother.

Innovations, HIV testing, HIV tests, Prenatal diagnosis

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Understanding and managing HELLP syndrome: The integral role of aggressive glucocorticoids for mother and child

Article Abstract:

Available literature on HELLP syndrome is reviewed and summarized to understand the impact of corticosteroids in the management of the disorder, which constitutes an obstetric emergency due to its potential to cause considerable maternal morbidity and mortality. It is concluded that the aggressive use of potent glucocorticoids in treatment of patients with HELLP syndrome results in maternal-fetal benefit.

United States, Risk factors, Drug therapy, Corticosteroids, HELLP syndrome, Corticosteroid drugs

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Maternal-fetal transfer and amniotic fluid accumulation of protease inhibitors in pregnant women who are infected with human immunodeficiency virus

Article Abstract:

Placental transfer and amniotic fluid concentration of protease inhibitors given to pregnant women who are infected with human immunodeficiency virus are investigated. The results indicate that placental transfer of human immunodeficiency virus protease inhibitors is generally low and may differ greatly according to the molecule.

Diagnosis, Maternal-fetal exchange, Protease inhibitors, HIV patients

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