The effect of fecal occult-blood screening on the incidence of colorectal cancer

Article Abstract:

Fecal occult blood screening every year or every two years may reduce the incidence of colorectal cancer, according to a study of 46,551 people. In the groups that were screened every one or two years, the incidence of colorectal cancer was about 20% lower during an 18-year follow-up. This probably occurs because people who test positive have precancerous polyps removed.

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Reducing mortality from colorectal cancer by screening for fecal occult blood

Article Abstract:

Annual screening for colorectal cancer with a fecal occult blood test could reduce mortality from the disease by 33%. Of 46,551 men and women between 50 and 80 years old, approximately 15,000 were screened annually, 15,000 were screened every two years and 15,000 were never screened. Those who had a positive test were referred for colonoscopy. They were followed for 13 years. Over the years the incidence of colorectal cancer was approximately the same in all three groups. However, after 13 years, the mortality rate in the annually screened individuals had dropped 33%. In addition, only 33% had advanced Dukes' stage D cancer, while 65% of those who were never screened had Dukes' stage D cancer. The five-year survival rate in individuals with Dukes' stage D cancer was only 2.4%, compared to survival rates of 94.3% to 56.6% in those with Dukes' stages A through C, respectively.

Evaluation, Patient outcomes, Mortality, Medical screening, Health screening

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Folic acid for the prevention of colorectal adenomas

Article Abstract:

A clinical trial carried out to observe the safety and efficiency of folic acid supplements to prevent colorectal adenomas is presented. Its result states that it does not reduce the risk but increase the risk of having colorectal adenomas.

Health aspects, Risk factors, Folic acid, Clinical report

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