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The effect of intermittent-release intraperitoneal chemotherapy on wound healing

Article Abstract:

Carboplatin may be an effective intraabdominal chemotherapeutic drug instilled immediately following surgery to remove ovarian cancer. Researchers tested the effect of intraabdominal carboplatin, Taxol, or saline solution in 70 rats after abdominal surgery in terms of adhesion formation and wound strength. None of the substances caused undue adhesion formation. Wound thickness and wound strength were significantly lower in animals receiving Taxol than in those receiving carboplatin. Carboplatin may be a more beneficial chemotherapy in humans immediately following removal of cancerous tumors than Taxol because Taxol seriously reduces white blood cell levels.

Author: Hopkins, Michael P., von Gruenigen, Vivian E., Holda, Sheri, Weber, Brad
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1997
Physiological aspects, Ovarian cancer, Chemotherapy, Wound healing, Carboplatin

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The impact of obesity and age on quality of life in gynecologic surgery

Article Abstract:

The effect of early stage endometrial cancer, age, and obesity on quality of life (QOL) is studied. Results suggest that women with early endometrial cancer have similar changes in QOL as those who received surgery for benign disease, while obese and elderly women have domain alterations.

Author: Gil, Karen M., Hopkins, Michael P., Gruenigen, Vivian E. von, Frasure, Heidi E., Jenison, Eric L.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2005
United States, Health aspects, Patient outcomes, Diagnosis, Obesity, Endometrial cancer, Gynecology, Operative, Gynecological surgery

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