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The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions

Article Abstract:

Antiepileptic drugs (AED) are commonly prescribed for nonepileptic conditions. The molecular and cellular mechanisms through which AEDs act to protect against seizures are reviewed and the actions of AEDs in diverse other conditions for which they are prescribed are considered.

Author: Loscher, Wolfgang, Rogawski, Michael A.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Anticonvulsant Preparations, Dosage and administration, Anticonvulsants, Migraine

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C[a.sup.2+] channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

Article Abstract:

Hereditary hemochromatis is a disorder common to people of Celtic origin, a condition where iron in the body accumulates in parenchymal tissues causing organ failure. This article explains a new mechanism to reverse this iron overload by using calcium channel blockers.

Author: Hentze, Matthias W., Muckenthaler, Martina U., Weiss, Guenter, Ludwiczek, Suzanne, Theurl, Milan, Kiss, Judit, Theurl, Igor, Paulmichl, Markus, Jakab, Martin, Ritter, Markus, Mair, Sabine M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Calcium Antagonists, Diagnosis, Genetic aspects, Calcium channel blockers, Iron metabolism disorders

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Fish oil fix

Article Abstract:

Fish oil has anti-inflammatory properties, however for years the mechanism has remained obscure. This mechanism is beginning to come in focus and aspirin might feed into the system by promoting the production of lipid mediators derived from the oil.

Author: Stenson, William F., Prescott, Stephen M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
Animal and marine fats and oils, Fish & Marine Oils, Rendering and Meat Byproduct Processing, Fish Liver Oils, Lipid membranes, Fish oils

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Subjects list: Care and treatment, Research, United States, Health aspects
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