Celecoxib and rofecoxib: the role of COX-2 inhibitors in dental practice

Article Abstract:

COX-2 inhibitors such as Celebrex and Vioxx may be helpful in treating dental pain and have fewer gastrointestinal side effects than non-steroidal anti-inflammatory drugs (NSAIDs). Vioxx acts more quickly and may be useful for treating pain after surgery.

Health aspects, Drug therapy, Pain, COX-2 inhibitors, Celebrex (Medication), Vioxx (Medication)

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The pharmacokinetics and cardiovascular effects of high-dose articaine with 1:100,000 and 1:200,000 epinephrine

Article Abstract:

Details of a clinical trial investigating the pharmacokinetics and cardiovascular effects of a high dose of articaine, with different dilutions of epinephrine, are presented. Articaine is used as a dental local anesthetic.

United States, Science & research, HEALTH SERVICES, All Other Miscellaneous Ambulatory Health Care Services, Disease Testing Programs, Research, Clinical trials, Anesthesia in dentistry, Dental anesthesia, Epinephrine, Drug evaluation, Articaine, Pharmacokinetics

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Adverse drug interactions in dental practice: professional and educational implications

Article Abstract:

Most of the drugs used by dentists are probably safe. Drugs used most often by dentists include painkillers, antibiotics, sedatives, local anesthetics and drugs that constrict blood vessels. Most of these drugs are given as a single dose for one time only, or at most, for 5 to 10 days. Most dental procedures are elective, so the dentist can schedule the appointment for a time when a drug interaction is less likely. Dentists can report any suspected drug reactions to the FDA's MEDWatch program.

Analysis, Complications and side effects, Practice, Dentistry, Drug interactions, Adverse drug reactions

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