Timing of labor induction after premature rupture of membranes between 32 and 36 weeks' gestation

Article Abstract:

Thirty-four weeks appears to be the best time to deliver a pregnant woman who has had premature rupture of membranes. Once a woman's membranes rupture, it is best to deliver the baby, but premature birth also has serious consequences. Researchers evaluated infant outcomes in 236 pregnancies complicated by premature rupture of membranes between 32 and 36 weeks. Infants born 34 weeks or later had much fewer complications than infants born before 34 weeks. Most pregnancies did not last longer than one week once the membranes ruptured.

Care and treatment, Planning, Prognosis, Premature rupture of membranes, Premature rupture of the membrane, Premature birth, Labor, Induced (Obstetrics), Induced labor

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Outcomes after expectant management of extremely preterm premature rupture of the membranes

Article Abstract:

In a study, the antepartum and ultrasound databases for patients with extremely preterm premature premature rupture of the membranes (EPPROM) are queried and data on pregnancy outcome and short-term neonatal outcomes were collected. It was concluded that although significant pregnancy prolongation after previable PPROM occurs in many cases, neonatal outcomes remain poor.

Research and Development in the Physical, Engineering, and Life Sciences, Research and Testing Services, Gynecological R&D, Pregnancy, Complications of, Pregnancy complications, Gynecological research

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Placental expression of enzymes regulating prostaglandin synthesis and degradation

Article Abstract:

The study characterized placental expression of the prostaglandin synthase enzymes cyclooxygenase (COX) -1 and -2 and prostaglandin dehydrogenase (PGDH, a degrading enzyme). It is concluded that placental COX-1 RNA at delivery decreases with advancing gestational age and with oxytocin use at term.

United States, Prostaglandins, Prostaglandin synthesis, Placental diseases, Placenta diseases, Cyclooxygenases

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