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Tissue-specific estrogens - the promise for the future

Article Abstract:

The reduced estrogen level in postmenopausal women is thought to increase their risk of cardiovascular disease and fractures from osteoporosis. Estrogen is critical in the function of bone and reproductive organs. Less than 20% of postmenopausal women take estrogen, likely because of uncomfortable side effects and an increased risk of cancer. Raloxifene is an estrogen-receptor modulator shown to increase bone density and improve the cholesterol profile, like estrogen, without apparent changes in the breasts and uterus. Such drugs may provide important benefits with fewer side effects.

Author: Hajj Fuleihan, Ghada El-
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Care and treatment, Innovations, Hormone therapy, Postmenopausal women, Estrogen, Estrogen receptors

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Quinonoid metal complexes: Toward molecular switches

Article Abstract:

The quinoid metal complexes are potentially very interesting molecular-based materials because they couple charge distribution bistability for magnetic proplutes. The systems offers exciting properties to be measured on individual molecules with STM and related techniques when organized properly on suitable surfaces.

Author: Gatteschi, Dante, Sorace, Lorenzo, Dei, Andrea, Sangregorio, Claudio
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Cobalt Compounds, Usage, Quinone, Quinones, Scanning tunneling microscopy, Coordination compounds, Magnetic properties, Chemical properties

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Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same?

Article Abstract:

A drug called strontium ranelate may be effective for treating osteoporosis, according to a study published in 2004. Strontium was used to treat osteoporosis in the 1950s, but was gradually replaced by safer drugs. This form of strontium does not appear to have the side effects of earlier strontium compounds.

Author: Hajj Fuleihan, Ghada El-
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Strontium & Compounds, Editorial, Drug therapy, Osteoporosis, Strontium compounds

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