Total plasma homocysteine and cardiovascular risk profile: the Hordaland homocysteine study

Article Abstract:

Elevated blood levels of homocysteine appear to be related to several factors associated with an increased risk of coronary heart disease. Homocysteine is a compound that occurs naturally in the human body. Researchers gave a general physical exam to 16,176 people residing in Hordaland County, Western Norway and measured their blood levels of homocysteine. Participants were also asked about their smoking and eating habits and their level of physical activity. Smokers had higher blood levels of homocysteine and the level increased as the number of cigarettes smoked increased. Homocysteine levels were also higher in those with high blood pressure and elevated cholesterol. Homocysteine levels were lower in those who engaged in regular physical activity. Homocysteine levels were higher in men than in women and increased with increasing age.

Physiological aspects, Heart diseases, Smoking, Exercise, Exercise physiology

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Plasma homocysteine levels and mortality in patients with coronary artery disease

Article Abstract:

Elevated blood levels of homocysteine may increase the risk of death in patients with coronary artery disease. Homocysteine is a naturally occurring amino acid. Researchers followed 587 patients with a history of coronary artery disease and past blood homocysteine tests. After four years, 25% of the patients with elevated homocysteine levels had died, compared to 4% of those with normal levels. This increased risk of death remained even after adjusting for other risk factors. Mortality rates progressively increased as blood homocysteine levels increased. Homocysteine may increase the risk of blood clot formation in coronary arteries.

Patient outcomes, Mortality, Coronary heart disease, Death

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Homocysteine lowering and cardiovascular events after acute myocardial infarction

Article Abstract:

The efficacy of homocysteine-lowering treatment with B vitamins was evaluated for secondary prevention in patients with acute myocardial infarction. It was seen that treatment with B vitamins did not lower the risk of recurrent cardiovascular disease after acute myocardial infarction.

United States, Care and treatment, Cardiovascular diseases

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