Transient acute depression induced by high-frequency deep-brain stimulation

Article Abstract:

Researchers report the case of a 65-year-old woman who experienced an episode of depression shortly after high-frequency brain stimulation. Electric stimulation of an area of the brain called the basal ganglia is sometimes used to treat people with Parkinson's disease. She had electrodes implanted in her basal ganglia on both sides to treat Parkinson's disease. Five seconds after her left brain was stimulated, she appeared sad and four minutes later was exhibiting the symptoms of severe depression. One minute after the stimulation stopped, she was laughing and appeared to be normal. Only stimulation to her left brain caused these symptoms.

Care and treatment, Complications and side effects, Parkinson's disease, Parkinson disease

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Parkinson's disease, depression, and electrical stimulation of the brain

Article Abstract:

A 1999 report suggests that there may be an area in the brain that produces symptoms of depression when stimulated. The report discusses the case of a woman with no history of depression who was treated with electrical stimulation of her brain for severe Parkinson's disease. When a small area in her left hemisphere called the substantia nigra was stimulated, within five minutes she displayed all the symptoms of depression. Her mode quickly improved when the stimulation stopped. Electrical stimulation of the brain might be used to treat psychological disorders and drug addiction.

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Costs to society of family caregiving for patients with end-stage Alzheimer's disease

Article Abstract:

Alzheimer's disease costs American business about $61 billion each year. About half of this cost is lost productivity because caregivers must quit their jobs or cut back their work hours to care for family members who have Alzheimer's disease. Many caregivers become depressed because of the enormous burden they must carry.

Economic aspects, Caregivers, Alzheimer's disease

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