Transmissible spongiform encephalopathies, amyloidoses and yeast prions: common threads?

Article Abstract:

Research presented concerns the parallels between mammalian transmissible spongiform encephalopathy, yeast proteins, and other protein-folding or aggregation diseases. Topics addressed include the role of prions in the propagation of infectious agents.

United States, Protein folding

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A novel erythroid-specific marker of transmissible spongiform encephalopathies

Article Abstract:

The pathology of transmissible spongiform encephalopathies (TSEs) are investigated in order to identify a molecular marker that may aid in the diagnosis and treatment of the disease. Results indicate that erythroid lineage cells are a common feature of TSEs, and they are detectable in accessible tissues.

United Kingdom, Statistical Data Included, Diseases, Nervous system, Bovine spongiform encephalopathy, Central nervous system diseases, Nerve degeneration, Encephalopathy

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A role for complement in transmissible spongiform encephalopathies

Article Abstract:

This article examines the development of prion diseases such as spongiform encephalopathies, focusing on how the infectious agents spread from the periphery to the neurons in the brain. Research on the complement system and its role in the uptake of transmissible spongiform encephalopathy-inducing agents is discussed.

Italy, Infection, Development and progression, Neurons, Complement (Immunology)

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