Very low-calorie diets
Article Abstract:
A very low-calorie diet (VLCD) may be an effective and safe method for short-term weight loss in moderately or severely obese individuals. Patients on a VLCD should be monitored closely by their physician. Researchers reviewed articles published in the medical literature between 1966 and 1992 on VLCDs, reducing diets and obesity. Most studies of VLCDs involved a comprehensive treatment program, including replacement of normal food with special food or a liquid formula, exercise, behavior modification and nutrition education . Patients on a VLCD lost an average of 1.5 to 2.5 kilograms (kg) per week, compared with an average loss of 0.4 to 0.5 kg per week for those on a standard low-calorie diet. Patients on a VLCD had an average total weight loss of 20 kg, compared to an average of 6 to 8 kg for those on a standard low-calorie diet. A VLCD may be less effective for long-term weight loss.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
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Nutrition
Article Abstract:
Soy protein appears capable of lowering blood cholesterol but it may be a challenge to develop soy foods that Americans will be willing to eat. A fat substitute named Olestra was introduced in certain snack foods. It is not digested by the body and therefore does not contribute any calories. However, it may deplete the body of important nutrients such as carotenoids. Obesity in America has risen 8% since 1980 and this has made diet pills very popular. Fenfluramine and phenteramine are widely prescribed, but are not without side effects. Regular exercise can reduce weight and also the risk of many obesity-related diseases.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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Recombinant Leptin for Weight Loss in Obese and Lean Adults: A Randomized, Controlled, Dose-Escalation Trial
Article Abstract:
Recombinant human leptin appears to cause weight loss in some obese people. Leptin is a naturally occurring hormone in the human body that seems to regulate fat metabolism. Researchers randomly assigned 54 normal-weight men and women and 73 obese men and women to give themselves daily subcutaneous injections of recombinant leptin or a placebo. Leptin caused weight loss in both groups and the more leptin was used, the more weight was lost. No side effects were noted except for mild reactions at the injection site.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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