Women's willingness to participate in microbicide trials in northern Thailand

Article Abstract:

The authors report on the attitudes of women in Thailand who were asked if they would take part in testing vaginal microbicides. A few were definitely positive, but most, while positive, wanted to think it over. Those who were willing pointed to being tested for AIDS among the benefits. Those who were reluctant indicated fears that involvement in the test would make her husband or partner feel safer, and encourage him to have more sex partners.

Testing, Prevention, Virus diseases, Viruses, Spermicides

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Safety and acceptability of the candidate microbicide carraguard in Thai women: Findings from a phase II clinical trial

Article Abstract:

A study was conducted in Chiang Fai, Northern Thailand to find out the safety and acceptability of vaginal application of Carraguard, a carrageenan-derived candidate microbicide gel. It was found that Carraguard can be used on the average of four times per week safely with or without sex and is acceptable to Thai women and presently ongoing in South Africa.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Antiinfective Preparations, Health aspects, Women, Anti-infective agents, Women's health, Carraguard (Contraceptive)

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HIV-1 Tat-based vaccines: From basic science to clinical trials

Article Abstract:

Several experiments conducted during the development of a new HIV-1 Tat vaccine which has entered phase I clinical trial evaluation were discussed. Based on preclinical data, the native Tat protein was chosen as a vaccine candidate for phase 1 preventive and therapeutic trial.

Product development, Clinical trials, Drug therapy, AIDS (Disease), AIDS vaccines

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