Cytotoxic activity of Coumarins from the fruits of Cnidium monnieri on Leukemia cell lines

Article Abstract:

Tests have shown that the ethanol extract of CmF (Cnidii monnieri Fructus) exhibited strong effects on human leukemia (HL-60), cervical carcinoma (HeLa) and colorectal carcinoma cells (CoLo 205). Osthol and imperatorin are indicated to be cytotoxic marker substances in the fruits of Cnidium monnieri.

Cancer cells, Cnidium

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Involvement of reactive oxygen species, but not mitochondrial permeability transition in the apoptotic induction of human SK-Hep-1 hepatoma cells by shikonin

Article Abstract:

Shikonin exhibits anti-cancer activity, but the underlying mechanisms are poorly understood. It is suggested that shikonin-induced apoptosis of SK-Hep-1 cells proceeds by an oxidative stress-mediated pathway.

Physiological aspects, Mitochondrial membranes, Mitochondrial membrane, Boraginaceae

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In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins

Article Abstract:

All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Mexico, Coumarin, Evaluation, Flavonoids, Flavones, Quinone, Quinones, Coumarins, Materia medica, Vegetable, Plant extracts, Alkaloids, Bioflavonoids, Antiprotozoan agents

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