Neurological impairment in violent schizophrenic inpatients

Article Abstract:

A group of 89 inpatients who were diagnosed as schizophrenic were divided into one of three groups according to the degree to which they exhibited violent tendencies. Level of violence was classified as high, low, or non-violent. Violence among the general population of psychiatric patients is frequently attributed to either neurological impairment or to a history of early abuse or deprivation. The authors examined these three groups with this in mind and tested them for five variables. The factors which were examined included demographic backgrounds, personal histories, results of EEG tests, and the appearance of neurological as well as neuropsychological abnormalities. No significant differences were found in the demographic or historical backgrounds of any of the groups. However, the group which was classified as most violent showed significant differences when their scores for neurologic and neuropsychologic factors were compared to the scores of other two groups. The most violent group exhibited more abnormalities, especially in areas of sensory and motor functions. Head trauma was ruled out as a possible cause of the differences, as was the theory that the neurologic abnormalities were a result of violent behavior rather than the cause. The authors concluded that a more severe form of schizophrenia exists which is characterized by neurological impairments and violence.

Psychological aspects, Abnormalities, Causes of, Central nervous system, Violence, Brain abnormalities

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Schizophrenia genetics: the quest for an anchor

Article Abstract:

The quest for a genetic basis for schizophrenia is far from over although there exist at least two viable methods for eventually achieving it. One method uses a biological basis which involves the choice of candidate genes from neurobiological systems while the other requires a full scan of human chromosomes by a particular set of markers. These methods coupled with the convergence of research efforts in related fields promise big advances in schizophrenic research.

Editorial, Evaluation, Genetic research

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Distributed disturbances in brain structure and function in schizophrenia

Article Abstract:

Research on schizophrenia shows that a specific brain abnormality may be the cause of symptoms, the consequence of an abnormality somewhere else, or a compensatory change. Different areas of the brain may be connected in ways that are only now being elucidated.

Physiological aspects

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