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Alternatives to 35-S as a label forthe differential display of eukaryotic messenger RNA

Article Abstract:

The differential display of mRNA is valuable for identifying altered gene expression in eukaryotic cells, but a potential health hazard was found. Alpha-[35S]dATP used as a label releases toxic levels of decomposition products during PCR. Alternatives are suggested and a reply is included.

Author: Trentmann, Stefan M., van der Knapp, Asther, Kende, Hans
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Usage, Messenger RNA, Sulfur

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RNA editing hints of a remarkable diversity in gene expression pathways

Article Abstract:

Research on the expression of mitochondrial genes in trypanosomatid protozoa has uncovered a reaction called RNA editing, an RNA processing reaction that transfers genetic information between RNAs. A model for RNA editing is presented.

Author: Seiwert, Scott D.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Physiological aspects, Genetic aspects, Genetic regulation, Trypanosoma

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Methylation and imprinting: from host defense to gene regulation?

Article Abstract:

Maternal and paternal gene expression may vary in the offspring. This is called gene imprinting. DNA methylation and the imprinting of genes may be connected perhaps in a causal relationship.

Author: Barlow, Denise P.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1993
Chromosome replication, Gametogenesis

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Subjects list: Research, Gene expression
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