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Locomotor circuits in the mammalian spinal cord

Article Abstract:

The new advances in understanding the mammalian central pattern generators (CPGs) are discussed by focusing on addressing the overall network structure as well as the identification of CPG neurons. The analysis has indicated that the mammalian locomotor CPG is distributed along the spinal cord, with a rostral-caudal gradient in rhymogenic potential.

Author: Kiehn, Ole
Publisher: Annual Reviews, Inc.
Publication Name: Annual Review of Neuroscience
Subject: Science and technology
ISSN: 0147-006X
Year: 2006
Analysis, Genetic aspects, Mammals, Molecular genetics, Structure

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An Essential Role for Ectodomain Shedding in Mammalian Development

Article Abstract:

The importance of ectodomain shedding activity is not defined, although much research on the topic has yielded physiological information about the activity. The lack of the metalloproteinase-disintegrin, TACE, is known to produce skin anomalies in mammals.

Author: Russell, William E., Johnson, Richard S., Lee, David C., Peschon, Jacques J., Sunnarborg, Susan W., Cerretti, Douglas Pat, Black, Roy A., Rauch, Charles T., Kozlosky, Carl J., Slack, Jennifer L., Wolfson, Martin F., Castner, Beverly J., Stocking, Kim L., Reddy, Pranitha, Nelson, Nicole, Fitzner, Jeffrey N., Paxton, Raymond J., March, Carl J., Boyce, Rogely W.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
Research, Cell adhesion, Metalloproteins

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Repairing the damaged spinal cord

Article Abstract:

The latest developments in repairing damaged spinal cords are discussed. A steroid called methylprednisolone has been found to preserve motor and sensory function if given at high doses within eight hours after spinal injury has occurred.

Author: McDonald, John W.
Publisher: Scientific American, Inc.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 1999
Care and treatment, Physiological aspects, Spinal cord injuries

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Subjects list: Spinal cord
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