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New Clues to How Neurons Strengthen Their Connections

Article Abstract:

Results of a new study indicate that the AMPA receptor for glutamate plays a key role in the strengthening of synapses. This strengthening process is known as long-term potentiation (LTP). Study results also seem to indicate that the changes that occur in LTP take place in the cell that receives the signal, rather than in the cell that dispenses the signal.

Author: BARINAGA, MARCIA
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1999
United States, Neural transmission, Synaptic transmission, Synapses, Neurotransmitter receptors

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Adaptation by hyperpolarization

Article Abstract:

A technique called whole-patch recording was used to determine how neurons in the visual cerebral cortex adapt to sensory stimulus. A fluid-filled electrode attached to a cell membrane continuously recorded a neuron's intracellular potential as it adapted to stimulus.

Author: Barlow, Horace
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Physiological aspects, Adaptation (Physiology), Physiological adaptation, Neurons, Neurophysiology, Neuroplasticity

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