New gene forges link between fragile site and many cancers

Article Abstract:

Cancer gene experts Carlo Croce, Kay Huebner and their colleagues have identified a gene they call FHIT which is damaged or missing in a broad range of cancers including lung, breast and colon cancer. The evidence suggests that the gene may be an important tumor suppressor.

Research, Discovery and exploration, Human chromosome abnormalities, Croce, Carlo, Heubner, Kay

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Teams tackle protein prediction

Article Abstract:

Some researchers believe that collaboration with other researchers will help improve the accuracy of predictions of three-dimensional protein structures. Researchers plan to pool the results of the Critical Assessment of Techniques for Protein Structure Prediction (CASP2).

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Filling in the blanks in the p53 protein structure

Article Abstract:

Researchers have solved the three-dimensional structure of a regulatory area on the amino terminus of the protein p53. The discovery provides important information on how p53 interacts with MDM2.

Physiological aspects

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