Science held back by ghosts of the past: Czech Republic

Article Abstract:

Research in the Czech Republic suffers from 25 years of repressionist policies and isolation under Soviet occupation. Universities do little research, positions have been filled based on ideology, funding is minimal and grants are blindly distributed without peer review.

Finance, Czech Republic, Cover Story, Science and technology policy, Science and state, Science policy, Czechoslovak Academy of Sciences

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HOX gene links limb, genital defects

Article Abstract:

The role that HOX genes play in humans has been largely unknown, but recent discoveries of what occurs when HOX mutates have recently been uncovered. One result is slightly abnormal fingers and toes, and another is limb and genital abnormalities.

Research, Gene mutations, Gene mutation, Human genetics, Homeobox genes

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No bones about a genetic switch for bone growth

Article Abstract:

Researchers have identified a gene named CBFA-1 which plays a key role in osteoblast differentiation and bone formation. A mutation in the gene is a factor in a skeletal disease called cleidocranial dysplasia.

Bones, Genetic aspects, Growth, Osteoblasts, Bone development, Cleidocranial dysplasia

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