Sequence and structural determinants of amyloid fibril formation
Article Abstract:
The sequence and structural determinants of protein aggregation in amyloid fibril formation and the factors that dominate the aggregation of unfolded peptides and proteins is described. The factors that pertain to the aggregation of partially structured states are reviewed and the ability of the even fully folded proteins states to aggregate into early oligomers in any case with no need to undergo significant conformational changes are presented.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2006
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Photocontrolling peptide alpha helices
Article Abstract:
Reversible optical control of protein structure and function offers the possibility of probing and manipulating individual proteins within the complex environment of a living cell. Reversible, photocontrolled peptide alpha helices is designed and synthesized as a first step towards creating artificial photocontrolled proteins.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2005
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Synchrotron radiolysis and mass spectrometry: a new approach to research on the actin cytoskeleton
Article Abstract:
Radiolytic protein footprinting along with mass spectrometry us developed and matures into a viable approach for analyzing protein structure and dynamics. The time-resolved dymaics of actin assembly and disassembly using footprinting is examined.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2004
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