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The Rotary Enzyme of the Cell: The Rotation of F1-ATPase

Article Abstract:

Researchers have proposed a model for the catalytic mechanism of F1-ATPase, the portion of the ATP synthase enzyme that performs ATP synthesis and degradation. The model includes a hypothesis that the enzyme rotates as it transmits energy. Experimental results that offer direct proof of the rotational model are discussed.

Author: Noji, Hiroyuki
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
Adenosine triphosphatase, Enzyme kinetics

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Cell division gatekeepers identified

Article Abstract:

Kinetochores control both the lining-up of chromosomes before cell division, and the timing of the separation. The findings by Richard McIntosh of the Univ. of Colorado is leading to much more detailed understanding of how cytoskeleton functions lead to healthy cell division.

Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
Cell division, Cytoskeleton

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Stretching is good for a cell

Article Abstract:

Cell health depends on attachment to other cells and to the extracellular matrix (ECM). A new research study found that cells attached to multiple dots on the ECM were less likely to undergo apoptosis that cells attached to one large dot.

Author: Ruoslahti, Erkki
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Cell interaction, Cell interactions, Cell adhesion

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Subjects list: Research, Physiological aspects
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