Exploring sex differences in the relationship between depressive symptoms and dementia incidence: prospective results from the PAQUID study

Article Abstract:

An analysis is presented of data obtained from the 1988 French study on normal and pathological aging to determine risk factors for dementia in depressed elderly men and women. Results indicate a correlation between proximal symptoms of depression and dementia in men, but the influence of vascular depression on dementia risk for this population is also considered.

France, Complications and side effects, Demographic aspects, Depression, Mental, Depression (Mood disorder), Sex factors in disease, Disease sex factors

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Estimating the true extent of cognitive decline in the old old

Article Abstract:

A study for the purpose of estimating the actual extent of cognitive decline in the old old has been carried out over a period of 9 years in 2,106 subjects using a brief measure and adjusting for attrition. It was found that cognitive decline in the very old has been underestimated considerably by longitudinal studies.

United Kingdom, Psychological aspects, Health aspects, Aging, Aged, Elderly, Statistical Data Included

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The tumor necrosis factor alpha-308G>a polymorphism is associated with dementia in the oldest old

Article Abstract:

The aim of the study is to test the hypothesis that the tumor necrosis factor (TNF) -308 G>A promoter gene polymorphism is a risk factor in age-related dementia and longevity. The results suggested that the TNF -308 GA genotype was associated with lower prevalence of dementia than the GG genotype in centenarians.

United States, Tumor necrosis factor, Tumour necrosis factor

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