Why does insulin resistance develop during maturation?

Article Abstract:

Insulin responsiveness in four-month-old, mature rats is much lower than in five-week-old rats at varying concentrations of insulin perfused into hindlimbs. The difference in skeletal muscle glucose uptake was most noticeable at highest concentrations. Insulin receptor binding, receptor-associated tyrosine kinase activity and autophosphorylation were measured as possible explanations for lowered glucose intake, but did not differ between young and mature rats. GLUT-4 glucose transporter content was high in the mature rats but possibly not in mature rats.

Causes of, Insulin resistance, Glucose

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Effect of aging on changes in plasma potassium during exercise

Article Abstract:

The elderly have a lower ability to reabsorb plasma potassium into muscles, which may have detrimental effects during prolonged exercise. The rate of increase and maximum concentration of plasma potassium (K+) for young men, non-athletic older men and a group of elderly master athletes was measured while subjects exercised to exhaustion on stationary bicycles. Although the older men showed faster rates of K+ increase, their peak concentrations did not rise as high as that of the younger subjects, because the elder group exercised for a shorter time.

Elderly, Research, Exercise, Exercise for the aged, Potassium in the body, Potassium (Nutrient)

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Hospice admission practices: where does hospice fit in the continuum of care?

Article Abstract:

Hospices offer multidisciplinary, holistic care in a variety of settings. An evaluation of selected hospice admission practices that could represent barriers to hospice use and the association between these practices and organizational characteristics is presented.

United States, Evaluation, Terminal care facilities, Hospices (Terminal care), Hospices

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