Pathophysiological characteristics of heart rate recovery in heart failure

Article Abstract:

A study was conducted to investigate clinical correlates of Heart Rate (HR) recovery in Heart Failure (HF) patients, which is associated with blunted HR recovery after exercise. HR recovery might be a clinically useful index identifying HF patients with distinct echocardiographic, neurohormonal, and hemodynamic characteristics, which might have implications for understanding of the pathophysiology of impaired HR recovery in HF as well as for the clinical evaluation of such patients.

Health aspects, Usage, Patient outcomes, Heart beat, Heart rate, Heart failure, Pulmonary function tests, Echocardiography, Neurohormones, Clinical report

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Muscle blood flow during exercise: the limits of reductionism

Article Abstract:

Regional blood flow during exercise increases according to complex mechanisms, not all of which are linked consistently. For example, the general rate of blood flow is not always but usually linked to the metabolic muscle action under observation. The reductionist method has failed to isolate a single factor responsible for such increases in blood flow. More integrated and innovative research efforts are required to explain exercise hyperemia.

Physiological aspects, Exercise, Exercise physiology, Blood vessels, Vasodilation, Regional blood flow

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Genotype-related differences in Beta(sub 2) adrenergic receptor density and cardiac function

Article Abstract:

A study aims to determine whether genetic variation of the Beta(sub 2) adrenergic (ADRB2) influence ADRB2 density and, consequently, resting cardiovascular function. Results suggest that the Arg16Gly polymorphism of the ADRB2 influences receptor density, which, in turn, contributes to resting differences in cardiac output and stroke volume.

Science & research, Research, Cardiac output, Epinephrine, Adrenergic receptors, Genetic variation

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