Regulation of MAC-1 (CD11b/CD18) expression on circulating granulocytes in endurance runners

Article Abstract:

Exhaustive exercise may be a mechanism for upward regulation of integrin adhesive receptors on granulocytes. A study to test the hypothesis that degranulation of granulocytes and regulation upward of the granulocyte integrin MA-1 (CD11b/CD18) are related to duration of exercise and /or its intensity has been carried out. Effects of body temperature/dehydration on MAC-1 expression have been investigated. The hypothesis that changes in leukocyte counts and changes in MAC1 expression with endurance exercise are independently regulated has been tested. Expression of CD11b on granulocytes was found to increase with intense endurance exercise, but not with moderate endurance work. The intense endurance activity can be either incremental maximal treadmill testing or competitive marathon running. The phenomenon might be partially responsible for greater adhesion of granulocytes to endothelial cells and it might help with tissue infiltration after endurance exercise. Eight male amateur runners in Germany were recruited for testing, which involved a treadmill test, a training run and a marathon race.

Germany, Physiological aspects, Endurance sports, Proteins, Cell receptors, Granulocytes

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Rehabilitation adherence in sport injury: Sport physiotherapists' perceptions

Article Abstract:

A qualitative methodology is used to understand the issue of adherence to sport injury rehabilitation and to gain insight into physiotherapists' perceptions and experiences of adherence issues in practice. It is concluded that adherence to rehabilitation is influenced by a number of factors and strategies.

Health aspects, Care and treatment, Analysis, Exercise therapy, Sports injuries, Health behavior, Health behaviour, Clinical report

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