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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Spindle saga

Article Abstract:

The mitotic spindle is a machine that segregates the duplicated chromosomes and is built from an array of protein tubes, the microtubules that assume a precise size and bipolar organization. Research teamwork for 15 years has concluded that spindle assembly results from the self-organization of chromosomes, microtubules and molecular motors.

Author: Karsenti, Eric
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
United States, Mitosis, Spindle (Cell division), Spindle (Cytoplasm)

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Molecular architecture of axonemal microtubule doublets revealed by cyro-electron tomography

Article Abstract:

A three-dimensional density map of intact microtubule doublets was obtained using cryo-electron tomography and image averaging. The 3nm resolution map so obtained provides insights into locations of particular proteins within the doublets and the structural features of the doublets that define their mechanical properties.

Author: Haixin Sui, Downing, Kenneth H.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
Physiological aspects, Observations, Eukaryotes, Microtubules, Electron beam computed tomography

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Subjects list: Research
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